Salvianolic Acid B Ameliorates Motor Dysfuntion in Spinal Cord Injury Rats
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چکیده
منابع مشابه
Salvianolic Acid B Ameliorates Motor Dysfuntion in Spinal Cord Injury Rats
Purpose: To evaluate the effect of salvianolic acid B (Sal B) treatment on the motor function of spinal cord injury (SCI) rat. Methods: SCI rats were modelled by contusion, and then received 10 mg/kg Sal B, or methylprednisolone, or phosphate-buffered saline (PBS) intraperitoneally daily for 4 weeks, two hours after the trauma occurred. During the treatment, footprint analysis (FA), inclined pl...
متن کاملStudy of Effect of Salvianolic Acid B on Motor Function Recovery in Rats with Spinal Cord Injury
In this study effect of salvianolic acid B was observed on motor function recovery of rats with spinal cord injury. 50 rats were selected and after inducing SCI their recovery under controlled conditions was studied using Sal B and PBS (as control). Both compounds were introduced intraperitoneally in respective groups of traumatic rats at the same time intervals for 28 days. It was observed tha...
متن کاملRetracted: Study of Effect of Salvianolic Acid B on Motor Function Recovery in Rats with Spinal Cord Injury
[This retracts the article DOI: 10.1155/2014/931850.].
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BACKGROUND Salvia miltiorrhiza (SM) Bunge is one of the widely-used Chinese medicinal herbs. Salvianolic acid B (Sal B), a bioactive compound isolated from the Chinese herb Radix Salviae Miltiorrhizae, has been reported to exhibit anti-inflammatory and anti-oxidantive effects. MATERIAL AND METHOD To study the cardioprotective effects of salvianolic acid B (Sal B) on acute myocardial ischemia ...
متن کاملAdenovirus-mediated delivery of GDNF ameliorates corticospinal neuronal atrophy and motor function deficits in rats with spinal cord injury.
The aim of the present study was to assess the effect of glial cell line-derived neurotrophic factor (GDNF) delivery mediated by a recombinant adenovirus (AdCMVgdnf or AdCMVlacZ) on the functional recovery and central neuronal atrophy in adult rats with spinal cord injury. Bilateral electrolytic lesions were made in the corticospinal tracts at the T10 vertebral level in a rat model. AdCMVgdnf o...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2014
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v13i1.8